BETRNet: Barrett's Esophagus Translational Research Network
- Recent selected publications in the field of BE and EAC
- Bioinformatic analyses of microRNA-targeted genes and microarray-identified genes correlated with Barrett's esophagus.
Authors: Lv J, Liu J, Guo L, Zhang J, Cheng Y, Chen C, Zhao H, Wang J
- The prevalence of gastric heterotopia of the proximal esophagus is underestimated, but preneoplasia is rare - correlation with Barrett's esophagus.
Authors: Peitz U, Vieth M, Evert M, Arand J, Roessner A, Malfertheiner P
- Toll-like receptors 1, 2, 4 and 6 in esophageal epithelium, Barrett's esophagus, dysplasia and adenocarcinoma.
Authors: Huhta H, Helminen O, Lehenkari PP, Saarnio J, Karttunen TJ, Kauppila JH
- Helicobacter pylori induces caudal-type homeobox protein 2 and cyclooxygenase 2 expression by modulating microRNAs in esophageal epithelial cells.
Authors: Teng G, Dai Y, Chu Y, Li J, Zhang H, Wu T, Shuai X, Wang W
- Unearthing the significance of buried intestinal metaplasia.
Authors: Setia N, Lauwers GY, Peña LR
- Association between circulating levels of sex steroid hormones and esophageal adenocarcinoma in the FINBAR Study.
Authors: Petrick JL, Falk RT, Hyland PL, Caron P, Pfeiffer RM, Wood SN, Dawsey SM, Abnet CC, Taylor PR, Guillemette C, Murray LJ, Anderson LA, Cook MB
- Insights into the genetics of gastroesophageal reflux disease (GERD) and GERD-related disorders.
Authors: Böhmer AC, Schumacher J
- Patients with Barrett's esophagus are hypersensitive to acid but hyposensitive to other stimuli compared with healthy controls.
Authors: Lottrup C, Krarup AL, Gregersen H, Ejstrud P, Drewes AM
- Transitional basal cells at the squamous-columnar junction generate Barrett's oesophagus.
Authors: Jiang M, Li H, Zhang Y, Yang Y, Lu R, Liu K, Lin S, Lan X, Wang H, Wu H, Zhu J, Zhou Z, Xu J, Lee DK, Zhang L, Lee YC, Yuan J, Abrams JA, Wang TC, Sepulveda AR, Wu Q, Chen H, Sun X, She J, Chen X, Que J
- Cardiac mucosa, Barrett's oesophagus and cancer of the gastro-oesophageal junction: what's in a name?
Authors: Spechler SJ
- ESOPHAGEAL CANCERS AND MODEL SYSTEMS.
Authors: Rustgi AK
- Diabetes in relation to Barrett's esophagus and adenocarcinomas of the esophagus: A pooled study from the International Barrett's and Esophageal Adenocarcinoma Consortium.
Authors: Petrick JL, Li N, Anderson LA, Bernstein L, Corley DA, El Serag HB, Hardikar S, Liao LM, Liu G, Murray LJ, Rubenstein JH, Schneider JL, Shaheen NJ, Thrift AP, van den Brandt PA, Vaughan TL, Whiteman DC, Wu AH, Zhao WK, Gammon MD, Cook MB
- Alterations to the Esophageal Microbiome Associated with Progression from Barrett's Esophagus to Esophageal Adenocarcinoma.
Authors: Snider EJ, Compres G, Freedberg DE, Khiabanian H, Nobel YR, Stump S, Uhlemann AC, Lightdale CJ, Abrams JA
- Flow based single cell analysis of the immune landscape distinguishes Barrett's esophagus from adjacent normal tissue.
Authors: Sen M, Hahn F, Black TA, DeMarshall M, Porter W, Snowden E, Yee SS, Tong F, Ferguson M, Fleshman EN, Nakagawa H, Falk GW, Ginsberg GG, Kochman ML, Blaesius R, Rustgi AK, Carpenter EL
- Calibration of fluorescence imaging for tumor surgical margin delineation: multistep registration of fluorescence and histological images.
Authors: Jiang Y, Girard EJ, Pakiam F, Seibel EJ
- High-resolution genomic alterations in Barrett's metaplasia of patients who progress to esophageal dysplasia and adenocarcinoma.
Authors: Sepulveda JL, Komissarova EV, Kongkarnka S, Friedman RA, Davison JM, Levy B, Bryk D, Jobanputra V, Del Portillo A, Falk GW, Sonett JR, Lightdale CJ, Abrams JA, Wang TC, Sepulveda AR
- High-Fat Diet Accelerates Carcinogenesis in a Mouse Model of Barrett's Esophagus via Interleukin 8 and Alterations to the Gut Microbiome.
Authors: Münch NS, Fang HY, Ingermann J, Maurer HC, Anand A, Kellner V, Sahm V, Wiethaler M, Baumeister T, Wein F, Einwächter H, Bolze F, Klingenspor M, Haller D, Kavanagh M, Lysaght J, Friedman R, Dannenberg AJ, Pollak M, Holt PR, Muthupalani S, Fox JG, Whary MT, Lee Y, Ren TY, Elliot R, Fitzgerald R, Steiger K, Schmid RM, Wang TC, Quante M
- Systems Biology Analyses Show Hyperactivation of Transforming Growth Factor-β and JNK Signaling Pathways in Esophageal Cancer.
Authors: Blum AE, Venkitachalam S, Ravillah D, Chelluboyina AK, Kieber-Emmons AM, Ravi L, Kresak A, Chandar AK, Markowitz SD, Canto MI, Wang JS, Shaheen NJ, Guo Y, Shyr Y, Willis JE, Chak A, Varadan V, Guda K
- Surgical approach and the impact of epidural analgesia on survival after esophagectomy for cancer: A population-based retrospective cohort study.
Authors: Cummings Iii KC, Kou TD, Chak A, Schluchter MD, Margevicius S, Cooper GS, Meropol NJ, Perry Y, Linden PA, Cummings LC
- Detection of Premalignant Gastrointestinal Lesions Using Surface-Enhanced Resonance Raman Scattering-Nanoparticle Endoscopy.
Authors: Harmsen S, Rogalla S, Huang R, Spaliviero M, Neuschmelting V, Hayakawa Y, Lee Y, Tailor Y, Toledo-Crow R, Kang JW, Samii JM, Karabeber H, Davis RM, White JR, van de Rijn M, Gambhir SS, Contag CH, Wang TC, Kircher MF
- Constitutively Higher Level of GSTT2 in Esophageal Tissues From African Americans Protects Cells Against DNA Damage.
Authors: Ferrer-Torres D, Nancarrow DJ, Steinberg H, Wang Z, Kuick R, Weh KM, Mills RE, Ray D, Ray P, Lin J, Chang AC, Reddy RM, Orringer MB, Canto MI, Shaheen NJ, Kresty LA, Chak A, Wang TD, Rubenstein JH, Beer DG
- Three-Dimensional Organoids Reveal Therapy Resistance of Esophageal and Oropharyngeal Squamous Cell Carcinoma Cells.
Authors: Kijima T, Nakagawa H, Shimonosono M, Chandramouleeswaran PM, Hara T, Sahu V, Kasagi Y, Kikuchi O, Tanaka K, Giroux V, Muir AB, Whelan KA, Ohashi S, Naganuma S, Klein-Szanto AJ, Shinden Y, Sasaki K, Omoto I, Kita Y, Muto M, Bass AJ, Diehl JA, Ginsberg GG, Doki Y, Mori M, Uchikado Y, Arigami T, Avadhani NG, Basu D, Rustgi AK, Natsugoe S
- A biomarker panel predicts progression of Barrett's esophagus to esophageal adenocarcinoma.
Authors: Duits LC, Lao-Sirieix P, Wolf WA, O'Donovan M, Galeano-Dalmau N, Meijer SL, Offerhaus GJA, Redman J, Crawte J, Zeki S, Pouw RE, Chak A, Shaheen NJ, Bergman JJGHM, Fitzgerald RC
- Cryotherapy in the management of premalignant and malignant conditions of the esophagus.
Authors: Lal P, Thota PN
- 2017 David Sun Lecture: Screening and Surveillance of Barrett's Esophagus: Where Are We Now and What Does the Future Hold?
Authors: Falk GW
- Increasing Dietary Fiber Intake Is Associated with a Distinct Esophageal Microbiome.
Authors: Nobel YR, Snider EJ, Compres G, Freedberg DE, Khiabanian H, Lightdale CJ, Toussaint NC, Abrams JA
- Dual-modal in vivo fluorescence and photoacoustic imaging using a heterodimeric peptide.
Authors: Chen J, Gao Z, Li G, Wang TD
- Endoscopic therapy for Barrett's esophagus and early esophageal cancer: Where do we go from here?
Authors: Singh T, Sanaka MR, Thota PN
- Is Mass Screening for Barrett's Esophagus a Myth or Reality?
Authors: Thota PN, Chak A
- Role of endoscopic therapy in early esophageal cancer.
Authors: Malik S, Sharma G, Sanaka MR, Thota PN
- Targeted Optical Imaging Agents in Cancer: Focus on Clinical Applications.
Authors: Joshi BP, Wang TD
- New light on the pancreatic cyst conundrum.
Authors: Berger NA
- Evaluation of Lineage Changes in the Gastric Mucosa Following Infection With Helicobacter pylori and Specified Intestinal Flora in INS-GAS Mice.
Authors: Pinzon-Guzman C, Meyer AR, Wise R, Choi E, Muthupalani S, Wang TC, Fox JG, Goldenring JR
- Subtypes of Barrett's oesophagus and oesophageal adenocarcinoma based on genome-wide methylation analysis.
Authors: Yu M, Maden SK, Stachler M, Kaz AM, Ayers J, Guo Y, Carter KT, Willbanks A, Heinzerling TJ, O'Leary RM, Xu X, Bass A, Chandar AK, Chak A, Elliott R, Willis JE, Markowitz SD, Grady WM
- Multiplexed Targeting of Barrett's Neoplasia with a Heterobivalent Ligand: Imaging Study on Mouse Xenograft in Vivo and Human Specimens ex Vivo.
Authors: Chen J, Zhou J, Gao Z, Li X, Wang F, Duan X, Li G, Joshi BP, Kuick R, Appelman HD, Wang TD
- Molecular Evolution of Metaplasia to Adenocarcinoma in the Esophagus.
Authors: Grady WM, Yu M
- Evidence for GALNT12 as a moderate penetrance gene for colorectal cancer.
Authors: Evans DR, Venkitachalam S, Revoredo L, Dohey AT, Clarke E, Pennell JJ, Powell AE, Quinn E, Ravi L, Gerken TA, Green JS, Woods MO, Guda K
- Aspirin: the miracle drug?
Authors: Thota PN
- Detection of Mutations in Barrett's Esophagus Before Progression to High-Grade Dysplasia or Adenocarcinoma.
Authors: Stachler MD, Camarda ND, Deitrick C, Kim A, Agoston AT, Odze RD, Hornick JL, Nag A, Thorner AR, Ducar M, Noffsinger A, Lash RH, Redston M, Carter SL, Davison JM, Bass AJ
- Young Adult Cancer: Influence of the Obesity Pandemic.
Authors: Berger NA
- The Esophageal Organoid System Reveals Functional Interplay Between Notch and Cytokines in Reactive Epithelial Changes.
Authors: Kasagi Y, Chandramouleeswaran PM, Whelan KA, Tanaka K, Giroux V, Sharma M, Wang J, Benitez AJ, DeMarshall M, Tobias JW, Hamilton KE, Falk GW, Spergel JM, Klein-Szanto AJ, Rustgi AK, Muir AB, Nakagawa H
- Association of sporadic and familial Barrett's esophagus with breast cancer.
Authors: Chan MQ, Blum AE, Chandar AK, Emmons AMLK, Shindo Y, Brock W, Falk GW, Canto MI, Wang JS, Iyer PG, Shaheen NJ, Grady WM, Abrams JA, Thota PN, Guda KK, Chak A
- Cryotherapy for persistent Barrett's esophagus after radiofrequency ablation: a systematic review and meta-analysis.
Authors: Visrodia K, Zakko L, Singh S, Leggett CL, Iyer PG, Wang KK
- Targeting Epigenetics to Prevent Obesity Promoted Cancers.
Authors: Berger NA, Scacheri PC
- The Effect of Endoscopic Surveillance in Patients With Barrett's Esophagus: A Systematic Review and Meta-analysis.
Authors: Codipilly DC, Chandar AK, Singh S, Wani S, Shaheen NJ, Inadomi JM, Chak A, Iyer PG
- Use of Appropriate Surveillance for Patients With Nondysplastic Barrett's Esophagus.
Authors: Tavakkoli A, Appelman HD, Beer DG, Madiyal C, Khodadost M, Nofz K, Metko V, Elta G, Wang T, Rubenstein JH
- Vitamin D in esophageal cancer: Is there a role for chemoprevention?
Authors: Rouphael C, Kamal A, Sanaka MR, Thota PN
- Emerging Insights into the Esophageal Microbiome.
Authors: May M, Abrams JA
- Identifying DNA methylation biomarkers for non-endoscopic detection of Barrett's esophagus.
Authors: Moinova HR, LaFramboise T, Lutterbaugh JD, Chandar AK, Dumot J, Faulx A, Brock W, De la Cruz Cabrera O, Guda K, Barnholtz-Sloan JS, Iyer PG, Canto MI, Wang JS, Shaheen NJ, Thota PN, Willis JE, Chak A, Markowitz SD
- Recent Advances in Screening for Barrett's Esophagus.
Authors: Sami SS, Iyer PG
- Yield of Higher-Grade Neoplasia in Barrett's Esophagus With Low-Grade Dysplasia Is Double in the First Year Following Diagnosis.
Authors: Rubenstein JH, Waljee AK, Dwamena B, Bergman J, Vieth M, Wani S
- GUCY2C maintains intestinal LGR5+ stem cells by opposing ER stress.
Authors: Kraft CL, Rappaport JA, Snook AE, Pattison AM, Lynch JP, Waldman SA
- CXCR4 Is a Potential Target for Diagnostic PET/CT Imaging in Barrett's Dysplasia and Esophageal Adenocarcinoma.
Authors: Fang HY, Münch NS, Schottelius M, Ingermann J, Liu H, Schauer M, Stangl S, Multhoff G, Steiger K, Gerngroß C, Jesinghaus M, Weichert W, Kühl AA, Sepulveda AR, Wester HJ, Wang TC, Quante M
- Identification and validation of FGFR2 peptide for detection of early Barrett's neoplasia.
Authors: Zhou J, He L, Pang Z, Appelman HD, Kuick R, Beer DG, Li M, Wang TD
- Genomic regions associated with susceptibility to Barrett's esophagus and esophageal adenocarcinoma in African Americans: The cross BETRNet admixture study.
Authors: Sun X, Chandar AK, Canto MI, Thota PN, Brock M, Shaheen NJ, Beer DG, Wang JS, Falk GW, Iyer PG, Abrams JA, Venkat-Ramani M, Veigl M, Miron A, Willis J, Patil DT, Nalbantoglu I, Guda K, Markowitz SD, Zhu X, Elston R, Chak A
- Fragments of e-Cadherin as Biomarkers of Non-erosive Reflux Disease.
Authors: Jovov B, Reed CC, Shaheen NJ, Pruitt A, Ferrell K, Orlando GS, Djukic Z, Orlando RC
- Identification of a key role of widespread epigenetic drift in Barrett's esophagus and esophageal adenocarcinoma.
Authors: Luebeck EG, Curtius K, Hazelton WD, Maden S, Yu M, Thota PN, Patil DT, Chak A, Willis JE, Grady WM
- A pooled analysis of dietary sugar/carbohydrate intake and esophageal and gastric cardia adenocarcinoma incidence and survival in the USA.
Authors: Li N, Petrick JL, Steck SE, Bradshaw PT, McClain KM, Niehoff NM, Engel LS, Shaheen NJ, Risch HA, Vaughan TL, Wu AH, Gammon MD
- A nonrandomized trial of vitamin D supplementation for Barrett's esophagus.
Authors: Cummings LC, Thota PN, Willis JE, Chen Y, Cooper GS, Furey N, Bednarchik B, Alashkar BM, Dumot J, Faulx AL, Fink SP, Kresak AM, Abusneineh B, Barnholtz-Sloan J, Leahy P, Veigl ML, Chak A, Markowitz SD
- Scanning Fiber Angioscopy: A Multimodal Intravascular Imaging Platform for Carotid Atherosclerosis.
Authors: Savastano LE, Seibel EJ
- Dietary sugar/starches intake and Barrett's esophagus: a pooled analysis.
Authors: Li N, Petrick JL, Steck SE, Bradshaw PT, McClain KM, Niehoff NM, Engel LS, Shaheen NJ, Corley DA, Vaughan TL, Gammon MD
- Editorial: The Effect of Bias on Estimation of Improved Survival After Diagnosis of Barrett's Esophagus.
Authors: Zakko L, Visrodia K, Wang KK, Iyer PG
- Modeling Esophagitis Using Human Three-Dimensional Organotypic Culture System.
Authors: Laczkó D, Wang F, Johnson FB, Jhala N, Rosztóczy A, Ginsberg GG, Falk GW, Rustgi AK, Lynch JP
- Toward real-time quantification of fluorescence molecular probes using target/background ratio for guiding biopsy and endoscopic therapy of esophageal neoplasia.
Authors: Jiang Y, Gong Y, Rubenstein JH, Wang TD, Seibel EJ
- Multimodal laser-based angioscopy for structural, chemical and biological imaging of atherosclerosis.
Authors: Savastano LE, Zhou Q, Smith A, Vega K, Murga-Zamalloa C, Gordon D, McHugh J, Zhao L, Wang M, Pandey A, Thompson BG, Xu J, Zhang J, Chen YE, Seibel EJ, Wang TD
- The Origins of Gastric Cancer From Gastric Stem Cells: Lessons From Mouse Models.
Authors: Hayakawa Y, Fox JG, Wang TC
- Aspirin prevents NF-κB activation and CDX2 expression stimulated by acid and bile salts in oesophageal squamous cells of patients with Barrett's oesophagus.
Authors: Huo X, Zhang X, Yu C, Cheng E, Zhang Q, Dunbar KB, Pham TH, Lynch JP, Wang DH, Bresalier RS, Spechler SJ, Souza RF
- Screening and Preventive Strategies in Esophagogastric Cancer.
Authors: Zakko L, Lutzke L, Wang KK
- Risk of malignant progression in Barrett's esophagus indefinite for dysplasia.
Authors: Ma M, Shroff S, Feldman M, DeMarshall M, Price C, Tierney A, Falk GW
- Breath Testing for Barrett's Esophagus Using Exhaled Volatile Organic Compound Profiling With an Electronic Nose Device.
Authors: Chan DK, Zakko L, Visrodia KH, Leggett CL, Lutzke LS, Clemens MA, Allen JD, Anderson MA, Wang KK
- Altered glycosyltransferases in colorectal cancer.
Authors: Venkitachalam S, Guda K
- Goblet Cell Ratio in Combination with Differentiation and Stem Cell Markers in Barrett Esophagus Allow Distinction of Patients with and without Esophageal Adenocarcinoma.
Authors: Schellnegger R, Quante A, Rospleszcz S, Schernhammer M, Höhl B, Tobiasch M, Pastula A, Brandtner A, Abrams JA, Strauch K, Schmid RM, Vieth M, Wang TC, Quante M
- Global DNA methylation patterns in Barrett's esophagus, dysplastic Barrett's, and esophageal adenocarcinoma are associated with BMI, gender, and tobacco use.
Authors: Kaz AM, Wong CJ, Varadan V, Willis JE, Chak A, Grady WM
- Transposon mutagenesis identifies candidate genes that cooperate with loss of transforming growth factor-beta signaling in mouse intestinal neoplasms.
Authors: Morris SM, Davison J, Carter KT, O'Leary RM, Trobridge P, Knoblaugh SE, Myeroff LL, Markowitz SD, Brett BT, Scheetz TE, Dupuy AJ, Starr TK, Grady WM
- In vivo photoacoustic tomography of EGFR overexpressed in hepatocellular carcinoma mouse xenograft.
Authors: Zhou Q, Li Z, Zhou J, Joshi BP, Li G, Duan X, Kuick R, Owens SR, Wang TD
- Cleavage of E-Cadherin Contributes to Defective Barrier Function in Neosquamous Epithelium.
Authors: Runge TM, Shaheen NJ, Djukic Z, Hallquist S, Orlando RC
- Gastrin and upper GI cancers.
Authors: Hayakawa Y, Chang W, Jin G, Wang TC
- RNA Sequencing Identifies Transcriptionally Viable Gene Fusions in Esophageal Adenocarcinomas.
Authors: Blum AE, Venkitachalam S, Guo Y, Kieber-Emmons AM, Ravi L, Chandar AK, Iyer PG, Canto MI, Wang JS, Shaheen NJ, Barnholtz-Sloan JS, Markowitz SD, Willis JE, Shyr Y, Chak A, Varadan V, Guda K
- Intestinal Enteroids Model Guanylate Cyclase C-Dependent Secretion Induced by Heat-Stable Enterotoxins.
Authors: Pattison AM, Blomain ES, Merlino DJ, Wang F, Crissey MA, Kraft CL, Rappaport JA, Snook AE, Lynch JP, Waldman SA
- Linkage and related analyses of Barrett's esophagus and its associated adenocarcinomas.
Authors: Sun X, Elston R, Falk GW, Grady WM, Faulx A, Mittal SK, Canto MI, Shaheen NJ, Wang JS, Iyer PG, Abrams JA, Willis JE, Guda K, Markowitz S, Barnholtz-Sloan JS, Chandar A, Brock W, Chak A
- Association Between Germline Mutation in VSIG10L and Familial Barrett Neoplasia.
Authors: Fecteau RE, Kong J, Kresak A, Brock W, Song Y, Fujioka H, Elston R, Willis JE, Lynch JP, Markowitz SD, Guda K, Chak A
- Gastrin stimulates a cholecystokinin-2-receptor-expressing cardia progenitor cell and promotes progression of Barrett's-like esophagus.
Authors: Lee Y, Urbanska AM, Hayakawa Y, Wang H, Au AS, Luna AM, Chang W, Jin G, Bhagat G, Abrams JA, Friedman RA, Varro A, Wang KK, Boyce M, Rustgi AK, Sepulveda AR, Quante M, Wang TC
- Genomic similarity between gastroesophageal junction and esophageal Barrett's adenocarcinomas.
Authors: Ferrer-Torres D, Nancarrow DJ, Kuick R, Thomas DG, Nadal E, Lin J, Chang AC, Reddy RM, Orringer MB, Taylor JM, Wang TD, Beer DG
- A Tissue Systems Pathology Assay for High-Risk Barrett's Esophagus.
Authors: Critchley-Thorne RJ, Duits LC, Prichard JW, Davison JM, Jobe BA, Campbell BB, Zhang Y, Repa KA, Reese LM, Li J, Diehl DL, Jhala NC, Ginsberg G, DeMarshall M, Foxwell T, Zaidi AH, Lansing Taylor D, Rustgi AK, Bergman JJ, Falk GW
- A Molecular Clock Infers Heterogeneous Tissue Age Among Patients with Barrett's Esophagus.
Authors: Curtius K, Wong CJ, Hazelton WD, Kaz AM, Chak A, Willis JE, Grady WM, Luebeck EG
- Potential Role of the Microbiome in Barrett's Esophagus and Esophageal Adenocarcinoma.
Authors: Snider EJ, Freedberg DE, Abrams JA
- Biochemical and functional characterization of glycosylation-associated mutational landscapes in colon cancer.
Authors: Venkitachalam S, Revoredo L, Varadan V, Fecteau RE, Ravi L, Lutterbaugh J, Markowitz SD, Willis JE, Gerken TA, Guda K
- Predicting Barrett's Esophagus in Families: An Esophagus Translational Research Network (BETRNet) Model Fitting Clinical Data to a Familial Paradigm.
Authors: Sun X, Elston RC, Barnholtz-Sloan JS, Falk GW, Grady WM, Faulx A, Mittal SK, Canto M, Shaheen NJ, Wang JS, Iyer PG, Abrams JA, Tian YD, Willis JE, Guda K, Markowitz SD, Chandar A, Warfe JM, Brock W, Chak A
- Can endosheath technology open primary care doors to Barrett's esophagus screening by transnasal endoscopy?
Authors: Iyer PG, Chak A
- Diagnosing gastrointestinal illnesses using fecal headspace volatile organic compounds.
Authors: Chan DK, Leggett CL, Wang KK
- MicroRNA Expression Signatures During Malignant Progression From Barrett's Esophagus.
Authors: Bansal A, Gupta V, Wang K
- Outcomes after endoscopic versus surgical therapy for early esophageal cancers in an older population.
Authors: Cummings LC, Kou TD, Schluchter MD, Chak A, Cooper GS
- Rates and predictors of progression to esophageal carcinoma in a large population-based Barrett's esophagus cohort.
Authors: Krishnamoorthi R, Borah B, Heien H, Das A, Chak A, Iyer PG
- Gastrointestinal imaging in 2015: Emerging trends in endoscopic imaging.
Authors: Joshi BP, Wang TD
- Design and Synthesis of Near-Infrared Peptide for in Vivo Molecular Imaging of HER2.
Authors: Joshi BP, Zhou J, Pant A, Duan X, Zhou Q, Kuick R, Owens SR, Appelman H, Wang TD
- Tissue-specific patterns of gene expression in the epithelium and stroma of normal colon in healthy individuals in an aspirin intervention trial.
Authors: Thomas SS, Makar KW, Li L, Zheng Y, Yang P, Levy L, Rudolph RY, Lampe PD, Yan M, Markowitz SD, Bigler J, Lampe JW, Potter JD
- Methylated B3GAT2 and ZNF793 Are Potential Detection Biomarkers for Barrett's Esophagus.
Authors: Yu M, O'Leary RM, Kaz AM, Morris SM, Carter KT, Chak A, Chandar A, Willis JE, Moinova HR, Markowitz SD, Brenner DE, Anandabapasathy S, Westerhoff M, Wong CJ, Shaheen NJ, Chen Y, Barnholtz-Sloan JS, Grady WM
- Immature myeloid progenitors promote disease progression in a mouse model of Barrett's-like metaplasia.
Authors: Kong J, Sai H, Crissey MA, Jhala N, Falk GW, Ginsberg GG, Abrams JA, Nakagawa H, Wang K, Rustgi AK, Wang TC, Lynch JP
- Multimodal endoscope can quantify wide-field fluorescence detection of Barrett's neoplasia.
Authors: Joshi BP, Duan X, Kwon RS, Piraka C, Elmunzer BJ, Lu S, Rabinsky EF, Beer DG, Appelman HD, Owens SR, Kuick R, Doguchi N, Turgeon DK, Wang TD
- Autophagy levels are elevated in barrett's esophagus and promote cell survival from acid and oxidative stress.
Authors: Kong J, Whelan KA, Laczkó D, Dang B, Caro Monroig A, Soroush A, Falcone J, Amaravadi RK, Rustgi AK, Ginsberg GG, Falk GW, Nakagawa H, Lynch JP
- Physical function and quality of life in patients with chronic GvHD: a summary of preclinical and clinical studies and a call for exercise intervention trials in patients.
Authors: Fiuza-Luces C, Simpson RJ, Ramírez M, Lucia A, Berger NA
- Comparative diagnostic performance of volumetric laser endomicroscopy and confocal laser endomicroscopy in the detection of dysplasia associated with Barrett's esophagus.
Authors: Leggett CL, Gorospe EC, Chan DK, Muppa P, Owens V, Smyrk TC, Anderson M, Lutzke LS, Tearney G, Wang KK
- IGFBP2 modulates the chemoresistant phenotype in esophageal adenocarcinoma.
Authors: Myers AL, Lin L, Nancarrow DJ, Wang Z, Ferrer-Torres D, Thomas DG, Orringer MB, Lin J, Reddy RM, Beer DG, Chang AC
- MEMS-based multiphoton endomicroscope for repetitive imaging of mouse colon.
Authors: Duan X, Li H, Qiu Z, Joshi BP, Pant A, Smith A, Kurabayashi K, Oldham KR, Wang TD
- ENVE: a novel computational framework characterizes copy-number mutational landscapes in colorectal cancers from African American patients.
Authors: Varadan V, Singh S, Nosrati A, Ravi L, Lutterbaugh J, Barnholtz-Sloan JS, Markowitz SD, Willis JE, Guda K
- Paired exome analysis of Barrett's esophagus and adenocarcinoma.
Authors: Stachler MD, Taylor-Weiner A, Peng S, McKenna A, Agoston AT, Odze RD, Davison JM, Nason KS, Loda M, Leshchiner I, Stewart C, Stojanov P, Seepo S, Lawrence MS, Ferrer-Torres D, Lin J, Chang AC, Gabriel SB, Lander ES, Beer DG, Getz G, Carter SL, Bass AJ
- Association of Serum Levels of Adipokines and Insulin With Risk of Barrett's Esophagus: A Systematic Review and Meta-Analysis.
Authors: Chandar AK, Devanna S, Lu C, Singh S, Greer K, Chak A, Iyer PG
- MethyLight droplet digital PCR for detection and absolute quantification of infrequently methylated alleles.
Authors: Yu M, Carter KT, Makar KW, Vickers K, Ulrich CM, Schoen RE, Brenner D, Markowitz SD, Grady WM
- EGFR Overexpressed in Colonic Neoplasia Can be Detected on Wide-Field Endoscopic Imaging.
Authors: Zhou J, Joshi BP, Duan X, Pant A, Qiu Z, Kuick R, Owens SR, Wang TD
- The role of Dickkopf-3 overexpression in esophageal adenocarcinoma.
Authors: Wang Z, Lin L, Thomas DG, Nadal E, Chang AC, Beer DG, Lin J
- Editorial: moving towards the appropriate use of proton pump inhibitors.
Authors: Kurlander JE, Rubenstein JH
- Early TP53 alterations engage environmental exposures to promote gastric premalignancy in an integrative mouse model.
Authors: Sethi NS, Kikuchi O, Duronio GN, Stachler MD, McFarland JM, Ferrer-Luna R, Zhang Y, Bao C, Bronson R, Patil D, Sanchez-Vega F, Liu JB, Sicinska E, Lazaro JB, Ligon KL, Beroukhim R, Bass AJ
- Modeling Epithelial Homeostasis and Reactive Epithelial Changes in Human and Murine Three-Dimensional Esophageal Organoids.
Authors: Nakagawa H, Kasagi Y, Karakasheva TA, Hara T, Aaron B, Shimonosono M, Kijima T, Giroux V, Bailey D, Wilkins B, Abrams JA, Falk GW, Aceves SS, Spergel JM, Hamilton KE, Whelan KA, Muir AB
- Isoforms of RNF128 Regulate the Stability of Mutant P53 in Barrett's Esophageal Cells.
Authors: Ray D, Ray P, Ferrer-Torres D, Wang Z, Nancarrow D, Yoon HW, San Martinho M, Hinton T, Owens S, Thomas D, Jiang H, Lawrence TS, Lin J, Lagisetty K, Chang AC, Beer DG
- Current management of Barrett esophagus and esophageal adenocarcinoma.
Authors: Singh T, Sanghi V, Thota PN
- Generation and Characterization of Patient-Derived Head and Neck, Oral, and Esophageal Cancer Organoids.
Authors: Karakasheva TA, Kijima T, Shimonosono M, Maekawa H, Sahu V, Gabre JT, Cruz-Acuña R, Giroux V, Sangwan V, Whelan KA, Natsugoe S, Yoon AJ, Philipone E, Klein-Szanto AJ, Ginsberg GG, Falk GW, Abrams JA, Que J, Basu D, Ferri L, Diehl JA, Bass AJ, Wang TC, Rustgi AK, Nakagawa H
- Safety and Acceptability of Esophageal Cytosponge Cell Collection Device in a Pooled Analysis of Data From Individual Patients.
Authors: Januszewicz W, Tan WK, Lehovsky K, Debiram-Beecham I, Nuckcheddy T, Moist S, Kadri S, di Pietro M, Boussioutas A, Shaheen NJ, Katzka DA, Dellon ES, Fitzgerald RC, BEST1 and BEST2 study investigators
- Acceptability, Accuracy, and Safety of Disposable Transnasal Capsule Endoscopy for Barrett's Esophagus Screening.
Authors: Sami SS, Iyer PG, Pophali P, Halland M, di Pietro M, Ortiz-Fernandez-Sordo J, White JR, Johnson M, Guha IN, Fitzgerald RC, Ragunath K
- Lower Annual Rate of Progression of Short-Segment vs Long-Segment Barrett's Esophagus to Esophageal Adenocarcinoma.
Authors: Hamade N, Vennelaganti S, Parasa S, Vennalaganti P, Gaddam S, Spaander MCW, van Olphen SH, Thota PN, Kennedy KF, Bruno MJ, Vargo JJ, Mathur S, Cash BD, Sampliner R, Gupta N, Falk GW, Bansal A, Young PE, Lieberman DA, Sharma P
- Cystic fibrosis is associated with an increased risk of Barrett's esophagus.
Authors: Knotts RM, Solfisburg QS, Keating C, DiMango E, Lightdale CJ, Abrams JA
- Discovery, Validation, and Application of Novel Methylated DNA Markers for Detection of Esophageal Cancer in Plasma.
Authors: Qin Y, Wu CW, Taylor WR, Sawas T, Burger KN, Mahoney DW, Sun Z, Yab TC, Lidgard GP, Allawi HT, Buttar NS, Smyrk TC, Iyer PG, Katzka DA, Ahlquist DA, Kisiel JB
- Sarcopenia in aging, obesity, and cancer.
Authors: Ligibel JA, Schmitz KH, Berger NA
- Autophagy mitigates ethanol-induced mitochondrial dysfunction and oxidative stress in esophageal keratinocytes.
Authors: Chandramouleeswaran PM, Guha M, Shimonosono M, Whelan KA, Maekawa H, Sachdeva UM, Ruthel G, Mukherjee S, Engel N, Gonzalez MV, Garifallou J, Ohashi S, Klein-Szanto AJ, Mesaros CA, Blair IA, Pellegrino da Silva R, Hakonarson H, Noguchi E, Baur JA, Nakagawa H
- Best Practices in Surveillance for Barrett's Esophagus.
Authors: Triggs JR, Falk GW
- Epigenetic alterations in the gastrointestinal tract: Current and emerging use for biomarkers of cancer.
Authors: Grady WM, Yu M, Markowitz SD
- Clinical Risk Prediction Model for Neoadjuvant Therapy in Resectable Esophageal Adenocarcinoma.
Authors: Thota PN, Alkhayyat M, Gomez Cifuentes JD, Haider M, Bena J, McMichael J, Sohal DP, Raja S, Sanaka MR
- Tropism of SARS-CoV-2 for Barrett's Esophagus may Increase Susceptibility to Developing COVID-19.
Authors: Jin RU, Brown JW, Li QK, Bayguinov PO, Wang JS, Mills JC, Collaborators, Whelan SPJ, Fitzpatrick JAJ, Meeker AK
- Massively Parallel Sequencing of Esophageal Brushings Enables an Aneuploidy-Based Classification of Patients with Barrett's Esophagus
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- Tropism of SARS-CoV-2 for Barrett's Esophagus may Increase Susceptibility to Developing COVID-19
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- Clinical Risk Prediction Model for Neoadjuvant Therapy in Resectable Esophageal Adenocarcinoma
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- Immune determinants of Barrett's progression to esophageal adenocarcinoma
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- Epigenetic Alterations in the Gastrointestinal Tract: Current and Emerging Use for Biomarkers of Cancer
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- Best Practices in Surveillance for Barrett's Esophagus
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- Sarcopenia in aging, obesity, and cancer
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- Barrett's Esophagus and Esophageal Adenocarcinoma Biomarkers
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- Autophagy mitigates ethanol-induced mitochondrial dysfunction and oxidative stress in esophageal keratinocytes
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- The effect of short-course antibiotics on the resistance profile of colonizing gut bacteria in the ICU: a prospective cohort study
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- Genome-Scale Analysis Identifies Novel Transcript-Variants in Esophageal Adenocarcinoma
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- Notch Signaling Mediates Differentiation in Barrett's Esophagus and Promotes Progression to Adenocarcinoma
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- Generation and Characterization of Patient-Derived Head and Neck, Oral, and Esophageal Cancer Organoids
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- Family History of Colorectal or Esophageal Cancer in Barrett's Esophagus and Potentially Explanatory Genetic Variants
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- Modeling Epithelial Homeostasis and Reactive Epithelial Changes in Human and Murine Three-Dimensional Esophageal Organoids
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- Is the age of diagnosis of esophageal adenocarcinoma getting younger? Analysis at a tertiary care center
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- Early TP53 alterations engage environmental exposures to promote gastric premalignancy in an integrative mouse model
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- Outcomes of patients with submucosal (T1b) esophageal adenocarcinoma: a multicenter cohort study
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- Risk of Cancer in Patients With Barrett Esophagus
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- Resection of early esophageal neoplasms: The pendulum swings from surgical to endoscopic management
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- Isoforms of RNF128 Regulate the Stability of Mutant P53 in Barrett's Esophageal Cells
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- Current management of Barrett esophagus and esophageal adenocarcinoma
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- Gastroesophageal reflux GWAS identifies risk loci that also associate with subsequent severe esophageal diseases
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- Discovery, Validation, and Application of Novel Methylated DNA Markers for Detection of Esophageal Cancer in Plasma
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- ESOPHAGEAL CANCERS AND MODEL SYSTEMS
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- Diabetes in relation to Barrett's esophagus and adenocarcinomas of the esophagus: A pooled study from the International Barrett's and Esophageal Adenocarcinoma Consortium
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- Alterations to the Esophageal Microbiome Associated with Progression from Barrett's Esophagus to Esophageal Adenocarcinoma
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- Management of Barrett Esophagus Following Radiofrequency Ablation
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- Flow based single cell analysis of the immune landscape distinguishes Barrett's esophagus from adjacent normal tissue
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- Calibration of fluorescence imaging for tumor surgical margin delineation: multistep registration of fluorescence and histological images
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- Prevalence and Incidence of Intestinal Metaplasia and Dysplasia of Gastric Cardia in Patients With Barrett's Esophagus After Endoscopic Therapy
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- High-resolution genomic alterations in Barrett's metaplasia of patients who progress to esophageal dysplasia and adenocarcinoma
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- High-Fat Diet Accelerates Carcinogenesis in a Mouse Model of Barrett's Esophagus via Interleukin 8 and Alterations to the Gut Microbiome
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- Barrett's esophagus: novel strategies for screening and surveillance
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- Systems Biology Analyses Show Hyperactivation of Transforming Growth Factor-β and JNK Signaling Pathways in Esophageal Cancer
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- Surgical approach and the impact of epidural analgesia on survival after esophagectomy for cancer: A population-based retrospective cohort study
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- Detection of Premalignant Gastrointestinal Lesions Using Surface-Enhanced Resonance Raman Scattering-Nanoparticle Endoscopy
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- Clinical Outcomes Based on the Timing of Appearance of Visible Lesions in Barrett's Esophagus During Endoscopic Eradication Therapy
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- Constitutively Higher Level of GSTT2 in Esophageal Tissues From African Americans Protects Cells Against DNA Damage
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- Three-Dimensional Organoids Reveal Therapy Resistance of Esophageal and Oropharyngeal Squamous Cell Carcinoma Cells
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- A biomarker panel predicts progression of Barrett's esophagus to esophageal adenocarcinoma
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- Cryotherapy in the management of premalignant and malignant conditions of the esophagus
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- Cystic fibrosis is associated with an increased risk of Barrett's esophagus
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- Increasing Dietary Fiber Intake Is Associated with a Distinct Esophageal Microbiome
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- Increasing prevalence of high-grade dysplasia and adenocarcinoma on index endoscopy in Barrett's esophagus over the past 2 decades: data from a multicenter U.S. consortium
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- Dual-modal in vivo fluorescence and photoacoustic imaging using a heterodimeric peptide
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- Role of endoscopic therapy in early esophageal cancer
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- Tumor organoids to study gastroesophageal cancer: a primer
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- Massively Parallel Sequencing of Esophageal Brushings Enables an Aneuploidy-Based Classification of Patients With Barrett's Esophagus
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- Tropism of Severe Acute Respiratory Syndrome Coronavirus 2 for Barrett's Esophagus May Increase Susceptibility to Developing Coronavirus Disease 2019
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- Multiplexed endoscopic imaging of Barrett's neoplasia using targeted fluorescent heptapeptides in a phase 1 proof-of-concept study
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- Age of diagnosis in familial Barrett's associated neoplasia
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- Relationship of the Esophageal Microbiome and Tissue Gene Expression and Links to the Oral Microbiome: A Randomized Clinical Trial
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- Understanding the cellular origin and progression of esophageal cancer using esophageal organoids
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- Optimal Timing for Cancer Screening and Adaptive Surveillance Using Mathematical Modeling
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- Receipt of Serial Endoscopy Procedures Prior to Esophageal Adenocarcinoma Diagnosis Is Associated with Better Survival
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- NOTCH3 limits the epithelial-mesenchymal transition and predicts a favorable clinical outcome in esophageal cancer
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- Long-Term Quality of Life Following Endoscopic Therapy Compared to Esophagectomy for Neoplastic Barrett's Esophagus
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- Chaperones and Ubiquitin Ligases Balance Mutant p53 Protein Stability in Esophageal and Other Digestive Cancers
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- Cellular plasticity at the nexus of development and disease
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- ATF3 induces RAB7 to govern autodegradation in paligenosis, a conserved cell plasticity program
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- Computational modelling suggests that Barrett's oesophagus may be the precursor of all oesophageal adenocarcinomas
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- Impact of Fiber-Based Enteral Nutrition on the Gut Microbiome of ICU Patients Receiving Broad-Spectrum Antibiotics: A Randomized Pilot Trial
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- Stem cells and origins of cancer in the upper gastrointestinal tract
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- Wide-area transepithelial sampling for dysplasia detection in Barrett's esophagus: a systematic review and meta-analysis
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- Associations between urinary 3-indoxyl sulfate, a gut microbiome-derived biomarker, and patient outcomes after intensive care unit admission
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- Alcohol Metabolism Enriches Squamous Cell Carcinoma Cancer Stem Cells That Survive Oxidative Stress via Autophagy
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- Cellular Plasticity, Reprogramming, and Regeneration: Metaplasia in the Stomach and Beyond
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- Randomized Controlled Trial of the Gastrin/CCK<sub>2</sub> Receptor Antagonist Netazepide in Patients with Barrett's Esophagus
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- Proanthocyanidins mitigate bile acid-induced changes in GSTT2 levels in a panel of racially diverse patient-derived primary esophageal cell cultures
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- UBCH5 Family Members Differentially Impact Stabilization of Mutant p53 via RNF128 Iso1 During Barrett's Progression to Esophageal Adenocarcinoma
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- 3D Organoids: An Untapped Platform for Studying Host-Microbiome Interactions in Esophageal Cancers
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- Thin Layer-Protected Gold Nanoparticles for Targeted Multimodal Imaging with Photoacoustic and CT
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- Paligenosis: Cellular Remodeling During Tissue Repair
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- Phenotype Discovery and Geographic Disparities of Late-Stage Breast Cancer Diagnosis across U.S. Counties: A Machine Learning Approach
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- Abnormal TP53 Predicts Risk of Progression in Patients With Barrett's Esophagus Regardless of a Diagnosis of Dysplasia
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- Regulation of the double-stranded RNA response through ADAR1 licenses metaplastic reprogramming in gastric epithelium
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- Characterization of Prevalent, Post-Endoscopy, and Incident Esophageal Cancer in the United States: A Large Retrospective Cohort Study
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- Cranberry Polyphenols in Esophageal Cancer Inhibition: New Insights
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- CD73<sup>+</sup> Epithelial Progenitor Cells That Contribute to Homeostasis and Renewal Are Depleted in Eosinophilic Esophagitis
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- Understanding Compliance, Practice Patterns, and Barriers Among Gastroenterologists and Primary Care Providers Is Crucial for Developing Strategies to Improve Screening for Barrett's Esophagus
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- Novel DNA Methylation Biomarker Panel for Detection of Esophageal Adenocarcinoma and High-grade Dysplasia
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- Sex differences in esophageal cancer overall and by histological subtype
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- Outcomes for endoscopic submucosal dissection of pathologically staged T1b esophageal cancer: a multicenter study
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- Prediction of neoplastic progression in Barrett's esophagus using nanoscale nuclear architecture mapping: a pilot study
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- Endoscopic submucosal dissection vs. endoscopic mucosal resection for early Barrett's neoplasia in the West: a retrospective study
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- Multifocal Cryoballoon Ablation for Eradication of Barrett's Esophagus-Related Neoplasia: A Prospective Multicenter Clinical Trial
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- SYSMut: decoding the functional significance of rare somatic mutations in cancer
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- HNF4A Defines Molecular Subtypes and Vulnerability to TGFβ-pathway Targeted Therapies in Cancers of the Distal Esophagus
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- Stroma New Tune: Emerging Role of PKA in Maintaining Gastric Homeostasis
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- Novel DNA Methylation Biomarker Panel for Detection of Esophageal Adenocarcinoma and High-Grade Dysplasia
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- Impact of bariatric surgery on cancer risk reduction
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- HNF4A Defines Molecular Subtypes and Vulnerability to Transforming Growth Factor β-Pathway Targeted Therapies in Cancers of the Distal Esophagus
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- Deep-Learning-Based Real-Time and Automatic Target-to-Background Ratio Calculation in Fluorescence Endoscopy for Cancer Detection and Localization
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- Cell plasticity in regeneration in the stomach and beyond
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- The Ephrin B2 Receptor Tyrosine Kinase Is a Regulator of Proto-oncogene MYC and Molecular Programs Central to Barrett's Neoplasia
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- Gastroesophageal Reflux Disease Is Not a Great Screening Criterion: Time to Move on to Other Strategies for Controlling the Burden of Esophageal Adenocarcinoma
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- An Endoscopic and Histologic Study on Healing of Radiofrequency Ablation Wounds in Patients With Barrett's Esophagus
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- Detection of Barrett's neoplasia with a near-infrared fluorescent heterodimeric peptide
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- Molecular pathogenesis, targeted therapies, and future perspectives for gastric cancer
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- Surveillance in Barrett's Esophagus: Challenges, Progress and Possibilities
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- Surveillance in Barrett's Esophagus: Challenges, Progress, and Possibilities
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- Patient-derived three-dimensional culture techniques model tumor heterogeneity in head and neck cancer
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- Adenocarcinoma of the oesophagus: is it gastric cancer?
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- Discovery and Initial Characterization of Long Intergenic Non-coding RNAs Associated with Esophageal Adenocarcinoma
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